Is Dental Fluorosis Caused by Thyroid Hormone Disturbances?
نویسنده
چکیده
Although it has been known since 1917 that mottled dental enamel (later recognized as dental fluorosis—DF) is identical with that observed in thyroid dysfunction, disturbances of thyroid hormone metabolism during crucial periods of tooth development as the primary cause of DF have received very little consideration by dental researchers. New findings indicate that thyroid hormone metabolism is disturbed in peripheral tissue of children with DF, thereby helping to account for timing of events observed in DF and the delayed eruption of teeth in fluoridated areas and further suggesting the use of DF as a marker and diagnostic aid for iodine deficiency disorders.
منابع مشابه
Is Dental Fluorosis Caused by Thyroid Hormone Disturbances?
Although it has been known since 1917 that mottled dental enamel (later recognized as dental fluorosis—DF) is identical with that observed in thyroid dysfunction, disturbances of thyroid hormone metabolism during crucial periods of tooth development as the primary cause of DF have received very little consideration by dental researchers. New findings indicate that thyroid hormone metabolism is ...
متن کاملStudy of thyroid hormones free triiodothyronine (FT3), free thyroxine (FT4) and thyroid stimulating hormone (TSH) in subjects with dental fluorosis
OBJECTIVE Apart from its well-known deleterious dental and skeletal effects, fluoride excess can have toxic effects on many other tissues. Fluoride, when in excess, is known to interfere with thyroid gland function. Fluoride-induced thyroid disturbances similar to those observed in iodine deficiency state in spite of adequate iodine intake have been documented. Similar thyroid disturbances in i...
متن کاملA comparative study of fluoride ingestion levels, serum thyroid hormone & TSH level derangements, dental fluorosis status among school children from endemic and non-endemic fluorosis areas
The study was undertaken to determine serum/urinary fluoride status and comparison of free T4, free T3 and thyroid stimulating hormone levels of 8 to 15 years old children with and without dental fluorosis living in an endemic and non-endemic fluorosis area. A sample group of 60 male and female school children, with or without dental fluorosis, consuming fluoride-contaminated water in endemic f...
متن کاملDental fluorosis as a complication of hereditary diabetes insipidus: studies of six affected patients.
Hereditary diabetes insipidus is a rare endocrine disorder caused by a deficiency of the antidiuretic hormone, vasopressin. The disease is characterized by polyuria, extreme thirst, and polydipsia. In this study of six affected members from two families with hereditary diabetes insipidus, it was found that two children who drank water fluoridated at optimum levels developed moderate to severe f...
متن کاملDevelopment of Fluoride Toxicity including Cognitive Impairment with Reduced Iq: Pathophysiology, Interactions with Other Elements, and Predisposing and Protective Factors
The development of toxicity to the fluoride ion (F) may be complex and multifactorial with a number of pathophysiological pathways being possible, with the potential for interactions between toxins involving additivity, synergism, and antagonism, and with a number of other factors having predisposing and protective effects. In addition to cognitive impairment with a reduced intelligence quotien...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2004